The purpose of this study was to describe the specific contribution of individual ligaments to the stability of the distal tibia-fibula syndesmosis joint at the ankle. Since this was a study used 8 cadaveric lower leg specimens, readers need to exercise some caution when transferring the results to function when the muscles are intact. With this caution, the data provides insight into the mechanisms of injury to these structures during what is referred to as a “high ankle sprain.” The “high” refers to the joint just above the ankle between the tibia and fibula. The integrity of this joint is important to ankle (talo-crual) stability. Injuries to the syndesmotic ligaments require a different approach than the more common injuries to the lateral ankle ligaments.